正常人黃斑中央凹無血管區域面積分析

2023年12月22日發(作者：草房子作者簡介)

正常人黃斑中央凹無血管區域面積分析

許暢;毛曉春

【期刊名稱】《國際眼科雜志》

【年(卷),期】2017(17)3

【摘 要】·AIM:To measure the foveal avascular zone ( FAZ) area and to

investigate the characteristics of the FAZ area in normal eyes, using optical

coherence tomography ( OCT) angiography.

·METHODS:This was a

cross-ctional study. The FAZ area was measured in 69 participants, for a

total of 138 eyes, using RTVue-100 OCT. The relations between the FAZ

area and the potential factors were evaluated by univariate and

multivariate linear regression analysis. Differences between the right and

left eyes were calculated, and values were compared by means of a paired

t test. Pearson correlation analysis was performed to asss the

relationships of the FAZ area between the right and left eyes.

·RESULTS: The mean FAZ area was 0. 30 ± 0. 11mm2 in all subjects.

For the male subjects, the mean FAZ area was 0. 29±0.13mm2, and for the

female subjects 0.31±0. 09mm2, with no significant difference (t=-1.

346,P=0. 180). The FAZ area did not correlate with all the potential factors.

The mean FAZ area in the right eye was 0. 30 ± 0. 11mm2 , and in the left

eye was 0. 30 ± 0. 10mm2 ,with no significant difference ( P = 0. 943 ).

There was a strong correlation between the right and left eyes for the FAZ

area.

· CONCLUSION: OCT angiography is a noninvasive method of

visualizing and measuring the FAZ area in normal subjects. The FAZ area

does not correlate with old age, x and other factors. It shows significant

interocular symmetry in normal subjects.%目的：運用光學相干斷層掃描技術( optical coherence tomography,OCT)血流成像技術測量正常人黃斑中央凹無血管區域(foveal avascular zone,FAZ)面積并分析FAZ面積相關臨床特征。

方法：采用橫斷面研究。用RTVue-100光學相干斷層掃描血流成像技術測量健康研究對象的138眼FAZ面積。FAZ面積與相關因素的相關性用單因素和多因素線性回歸分析。采用配對t檢驗比較右眼與左眼FAZ面積的差異。 Pearson相關性分析雙眼FAZ面積的相關性。

結果：所有研究對象的平均FAZ面積為0.30±0.11mm2。男性研究對象平均FAZ面積為0.29±0.13mm2,而女性為0.31±0.09mm2,男性FAZ面積小于女性FAZ面積,但差異無統計學意義( t=-1.346, P=0.180)。 FAZ面積與年齡、性別等臨床基本資料無相關性。右眼平均FAZ面積為0.30±0.11mm2,左眼平均FAZ面積為0.30±0.10mm2,雙眼差異無統計學意義( P=0.943)。雙眼FAZ面積存在很強的相關性。

結論：OCT血流成像技術可清晰觀察并定量測量FAZ面積。 FAZ面積與老齡、性別等因素無關,雙眼FAZ面積呈對稱性特征。

【總頁數】5頁(P499-503)

【作 者】許暢;毛曉春

【作者單位】441021 中國湖北省襄陽市中心醫院眼科;441021 中國湖北省襄陽市中心醫院眼科

【正文語種】中 文

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